Merck announces positive Phase 3 data for neoantigen therapy: Can MRK break above $149.98?

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Merck stock edges lower to $148.84

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Andrey Mastykin

22.10.2026

Merck announces positive Phase 3 data for neoantigen therapy: Can MRK break above $149.98? — Merck stock edges lower to $148.84

Merck said it has posted positive Phase 3 results for its neoantigen therapy combined with its immunotherapy for resected stage IIB-IV melanoma, developed in partnership with Moderna. Shares edge lower on the day, trading at $148.84.

MRK price prediction

24H 0.05%

€151.33

48H -0.11%

€151.08

7D -0.31%

€150.78

1M 6.15%

€160.55

3M 15.14%

€174.15

6M 4.32%

€157.78

12M 27.58%

€192.96

Current price: €151.25 0.9500 0.63%

Closed 10/30

Daily range 150.50

152.10

Weekly range 142.05

152.10

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Highlights

Merck reports positive Phase 3 results for its individualized neoantigen therapy with immunotherapy in resected stage IIB-IV melanoma in partnership with Moderna.
Shares of Merck edge lower on the day, trading at $148.84.
77 of 110 analysts rate Merck stock a buy, 1 recommend selling, and the median price target is $163.

Merck announced positive Phase 3 data for its investigational individualized neoantigen therapy in combination with its immunotherapy. The results pertain to patients with completely resected stage IIB-IV melanoma. The development of the therapy is being carried out in collaboration with Moderna.

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Muted session move as bullish structure holds above major averages

The session opened with a gap down from the previous close at $149.88 to $147.11 as price action runs counter to the broader bullish daily structure. Shares of Merck remain above their MA-20, MA-50, and MA-200, maintaining overall bullish alignment despite a muted move against the prevailing trend. The nearest resistance is the weekly high at $149.98. Stoch RSI is in overbought territory, which limits the immediate potential for further upside.

Upside probability dominates as traders look for a close above resistance

A close above $149.98 would indicate buyers are willing to follow through on recent events. Merck stock opened sharply lower at $147.11 from the prior close of $149.88, partially retracing the gap during the session. The past week has seen a contained move within a narrow range, yet from here, traders face more than 80% probability of upside and less than 20% downside over the coming trading week, with an expected range of $145.95 to $151.72. A drop below $146.2 would show the move is being faded. On the weekly chart the longer-term picture stays firmly constructive.

Earlier, analysts noted that Merck’s bullish technical outlook was supported by pivotal clinical results in diabetic macular edema. The current update adds momentum with positive Phase 3 data in melanoma, and traders should now monitor whether shares can sustain levels above the weekly high at $149.98 to validate continued upside.

This material may contain third-party opinions, none of the data and information on this webpage constitutes investment advice according to our Disclaimer. While we adhere to strict Editorial Integrity, this post may contain references to products from our partners.

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