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Actinium Pharmaceuticals announced the commencement of its first in human Phase 1 trial evaluating ATNM-400, a HER3 targeted, non PSMA radiotherapy, in patients with metastatic castration resistant prostate cancer.
The update was shared during the ESMO2026 conference in Madrid. The study marks a step forward in exploring new treatment options for advanced prostate cancer using innovative radiotherapy approaches.
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Actinium previously delivered new updates on the clinical and preclinical progress of ATNM-400 in major cancer indications, as reported here. The company also presented preclinical efficacy data for ATNM-400 in lung, colorectal, and ovarian cancer at EANM26 in Vienna, detailed here. These developments highlight Actinium's continued focus on expanding the potential applications of ATNM-400.