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Venture Capital and Web3 Strategy from Arianna Simpson

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Venture Capital and Web3 Strategy from Arianna Simpson

Arianna Simpson, a general partner at Andreessen Horowitz (a16z crypto), continues to lead high-impact investments in early-stage blockchain infrastructure, DeFi, and consumer apps in 2025. She helped deploy a16z’s $4.5 billion crypto fund into sectors including zero-knowledge tech, gaming, and cross-chain liquidity systems. In 2024–25, Simpson led deals with LayerZero, Aztec, and on-chain identity startup Spruce, and she continues to push for inclusive founder representation in Web3.

Prior to joining a16z, Simpson founded Autonomous Partners, a crypto hedge fund, and held product and strategy roles at Facebook. She studied at Penn State and is widely recognized for her sharp insights into tokenomics, governance, and protocol incentives. Simpson is frequently cited in Fortune, Bloomberg, and CoinDesk, and serves as a board member or advisor to several high-growth blockchain startups. Her advocacy for crypto-native UX and privacy-preserving infrastructure has made her a key force in shaping the next wave of decentralized tech.

Stablecoins accelerate agent-forward transition in finance, Arianna Simpson notes

Yaroslav Dmytrenko
24.03.2026

Stablecoins accelerate agent-forward transition in finance, Arianna Simpson notes

Arianna Simpson highlights the rising influence of stablecoins as the world moves toward an agent-forward financial landscape. According to Simpson, stablecoins enable agents to transact similarly ...

Arianna Simpson: EF outlines new mandate and principles for Ethereum community

Jose Antonio Gastelum
14.03.2026

Arianna Simpson: EF outlines new mandate and principles for Ethereum community

The Ethereum Foundation (EF) has announced a new mandate outlining its principles and boundaries. Arianna Simpson, who has been involved in the Ethereum community since 2014, welcomed the ...

Arianna Simpson flags shift as stablecoins and on-chain identity emerge as crypto infrastructure

Yaroslav Dmytrenko
28.02.2026

Arianna Simpson flags shift as stablecoins and on-chain identity emerge as crypto infrastructure

The debate over whether crypto is dead has become outdated, according to Arianna Simpson. Simpson argues that withstanding several market cycles has moved the focus to which components of the ...

Arianna Simpson: Term sheets preempt investment decisions

Iryna Sazhynska
24.09.2025

Arianna Simpson: Term sheets preempt investment decisions

In a recent tweet, investor Arianna Simpson highlighted a key signal in the investment process: the arrival of a term sheet. She implies that when investors see a term sheet in their inbox, it ...

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