VC leadership, AI infrastructure, and open-source innovation by Alessio Fanelli
Alessio Fanelli is Partner and CTO-in-Residence at Decibel, a venture capital firm managing $525 million focused on developer platforms, data systems, and security infrastructure. Fanelli previously worked at 645 Ventures, where he supported investments in six startups including Panther Labs, Bigeye, and Oort. In 2022, he co-founded and now co-hosts the Latent Space podcast, which surpassed 600,000 downloads and 1 million newsletter readers by June 2025, ranking among the top ten technology podcasts. His investing activities at Decibel cover early-stage seed and Series A rounds, with more than a dozen deals completed since joining. Fanelli holds degrees in Computer Science and Engineering from Yale University. While his current portfolio centers on AI and software tooling, his podcast discussions often intersect with blockchain scalability and the developer ecosystem for decentralized applications. With active visibility in the infrastructure community, Fanelli brings perspective on how venture capital is shaping the overlap of AI, cloud, and blockchain engineering.