Nurix Therapeutics enrolls first patient in Phase 1b2 trial of oral BTK degrader for CLL

Nurix Therapeutics enrolls first patient in Phase 1b2 trial of oral BTK degrader for CLL
Nurix starts Phase 1b2 CLL trial

Nurix Therapeutics has announced enrollment of the first patient in its Phase 1b2 study investigating its oral BTK degrader, bexobrutideg, in combination with venetoclax for the treatment of chronic lymphocytic leukemia (CLL).

The study is being conducted in partnership with Roche and marks a significant milestone in Nurix Therapeutics' clinical development of targeted therapies for hematologic malignancies.

Nurix recently earned a $7 million milestone in its strategic collaboration with Pfizer focused on advancing degrader antibody therapies. The company also extended its oncology research partnership with Gilead Sciences by two years, securing a $10 million extension fee. These agreements highlight Nurix's ongoing engagement with major pharmaceutical partners.

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