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Agenus has announced the publication of results from UNICORN, its Phase 2 trial investigating BOT and BAL in preoperative colon cancer, in the journal Nature Medicine.
The data indicate deep responses in patients with microsatellite-stable (MSS) colon cancer and support continued development of ROBBIN, Agenus planned Phase 3 trial.
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Agenus previously reported a 72 percent pathologic complete response and 83 percent major response in its Phase 2 trial of dMMR colon cancer, according to company data. The company is also scheduled to announce third quarter 2026 financial results on November 5, as outlined in its recent earnings release. These milestones come as Agenus advances development of its pipeline in colon cancer.