Lexicon Pharmaceuticals presents Phase 2b results supporting 10 mg dose in DPNP at AAN 2026

Lexicon Pharmaceuticals presents Phase 2b results supporting 10 mg dose in DPNP at AAN 2026
Lexicon backs 10 mg dose at AAN

Lexicon Pharmaceuticals unveiled results from its Phase 2b PROGRESS trial at AAN 2026, supporting the advancement of a 10 mg dose into Phase 3 for diabetic peripheral neuropathic pain (DPNP).

The company also shared new preclinical data related to its ongoing research, reinforcing its commitment to addressing unmet needs in neuropathic pain. Further details can be accessed via Lexicon Pharmaceuticals official update.

Lexicon has previously shared new SOTA‑P‑CARDIA Chapter 2 trial data in HFpEF at ACC26. The company also reported SCORED trial results on cardiovascular outcomes in type 2 diabetes and kidney disease. These disclosures reflect Lexicon’s ongoing pipeline activity in metabolic and cardiovascular indications.

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