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Cullinan Therapeutics has unveiled initial clinical data for CLN-978, an investigational CD19xCD3 T cell engager, targeting patients with refractory systemic lupus erythematosus (SLE) and difficult-to-treat rheumatoid arthritis (RA) at the EULAR2026 conference.
The findings, shared in a poster presentation, mark a step forward for the development of potential therapies for patients with limited treatment options for these autoimmune diseases. Full details of the study and its implications remain closely monitored by the medical and investment communities.
Cullinan Therapeutics has previously pursued T cell engager therapies targeting B cells to address underlying mechanisms of autoimmune diseases, according to an earlier report on the company's experimental focus. In June, Cullinan said it would present early clinical data on CD19 and BCMA T cell engagers for autoimmune conditions at a scheduled meeting. These developments come as the company expands its pipeline in challenging autoimmune indications.