Pacific Biosciences of California compares Illumina TruPath and PacBio HiFi WGS using HG002 benchmark

Pacific Biosciences of California compares Illumina TruPath and PacBio HiFi WGS using HG002 benchmark
PacBio analyzes Illumina TruPath

Pacific Biosciences of California is examining how Illumina TruPath performs against its own PacBio HiFi whole genome sequencing technology using publicly available HG002 benchmark data.

The analysis compares read support, variant calling, phasing, methylation patterns, and the application of pangenome references in both sequencing approaches. Pacific Biosciences of California aims to provide the genomics community with transparent benchmarking using real-world data. The full comparison is available through the company’s latest post.

Pacific Biosciences of California recently launched Vega and SPRQ-Nx chemistry to increase sequencing speed, yield, and efficiency, according to a previous announcement. The company also introduced the HiFi Fit Kit, giving researchers access to custom sequencing resources in less than a minute, as detailed in a recent debut. These product rollouts follow ongoing efforts to benchmark performance in genomics technology.

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