Nicole DeTommaso: Most recent U.S. $1B startups use AI as core technology

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Yaroslav Dmytrenko

12.05.2026

Nicole DeTommaso: Most recent U.S. $1B startups use AI as core technology — AI powers most new U.S. $1B startups

Nicole DeTommaso analyzed the last 50 companies to achieve a $1 billion valuation in the U.S. using Scout from Harmonic.

According to her review, while 36% of these startups are AI-native, more than 60% leverage AI as a core technology across sectors such as defense and healthcare.

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DeTommaso has previously discussed how fund size shapes investment strategy and the need to align with investor objectives in her analysis of venture capital trends, available here. She has also advised aspiring VC professionals to focus on niche recruiting and clarify their value propositions in the sector, as detailed here. Her research frequently centers on specialized approaches within venture capital.

This material may contain third-party opinions, none of the data and information on this webpage constitutes investment advice according to our Disclaimer. While we adhere to strict Editorial Integrity, this post may contain references to products from our partners.

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