Pacific Biosciences of California urges lower DNA input for HiFi sequencing with new Ampli-Fi workflow

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28.05.2026

Pacific Biosciences of California urges lower DNA input for HiFi sequencing with new Ampli-Fi workflow — Pacific Biosciences addresses DNA input

Pacific Biosciences of California has addressed a key concern for laboratories by detailing how lower DNA input requirements can be achieved for HiFi sequencing using the Ampli-Fi workflow.

This update is part of the company’s Top 5 Questions series, aiming to help labs get started with reduced DNA input needs. The new workflow is expected to increase accessibility for laboratories that may have limited sample availability, making advanced sequencing technology more broadly usable across research settings.

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Pacific Biosciences of California recently introduced a sequencing method combining genetic and methylation detection in a single run. The company has also hosted a webinar on full-length 16S sequencing for microbiome research. These developments come as PacBio continues to update workflows for greater laboratory accessibility.

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