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Spyre Therapeutics, Inc. has launched its SPY772 program and begun the SKYLIGHT Phase 2 clinical trial targeting hidradenitis suppurativa (HS).
The study is designed to provide proof of concept for TL1A and IL-17A/F inhibition as a novel therapeutic approach in patients with HS, a chronic and debilitating skin condition. This move marks a significant step for the company in advancing innovative therapies within dermatology and autoimmune research. Additional information can be found in the company's recent press release and fact sheet.
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Spyre Therapeutics is also developing SPY002, a monoclonal antibody targeting TL1A for inflammatory bowel disease. The company recently attended the Leerink Partners Therapeutics Forum in Boston, where it held meetings with investors. These efforts reflect the firm's ongoing focus on advancing novel immunology therapies.