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Monte Rosa Therapeutics moves forward with plans to initiate a new Phase 2 study of MRT-2359 in combination with a second-generation androgen receptor (AR) inhibitor for patients with metastatic castration-resistant prostate cancer (mCRPC) harboring AR mutations.
Chief Medical Officer Filip Janku commented that updated data for MRT-2359 provides strong support for this next stage of clinical evaluation. The upcoming study aims to address unmet medical needs in a challenging patient subgroup and further explores the potential of targeted combination regimens in oncology.