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Biomea Fusion has completed chronic toxicity studies for Icovamenib, strengthening non-clinical support for progressing to chronic clinical dosing in its diabetes and obesity programs.
The company also released 52-week follow-up data from the COVALENT-112 (icovamenib | T1D) clinical trial, marking a key milestone in its pipeline. These updates signal continued momentum in Biomea Fusion strategy for advancing novel treatments targeting metabolic diseases.
Biomea Fusion previously launched participant enrollment in the COVALENT-212 clinical trial of icovamenib in type 2 diabetes. In earlier results, the company reported a 52 percent rise in C peptide AUC at week 12 in a Phase 2 trial for type 1 diabetes. That effect was sustained at week 52 in the same study.